ALR (GFER) (NM_005262) Human Mass Spec Standard

Specifications

Product Data
Description	GFER MS Standard C13 and N15-labeled recombinant protein (NP_005253)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC220589
Predicted MW	23.3 kDa
Protein Sequence	Sequence Link (showhide) >RC220589 representing NM_005262 Red=Cloning site Green=Tags(s) MAAPGERGRFHGGNLFFLPGGARSEMMDDLATDARGRGAGRRDAAASASTPAQAPTSDSPVAEDASRRRP CRACVDFKTWMRTQQKRDTKFREDCPPDREELGRHSWAVLHTLAAYYPDLPTPEQQQDMAQFIHLFSKFY PCEECAEDLRKRLCRNHPDTRTRACFTQWLCHLHNEVNRKLGKPDFDCSKVDERWRDGWKDGSCD TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_005253
RefSeq Size	2447
RefSeq ORF	615
Synonyms	ALR; ERV1; HERV1; HPO; HPO1; HPO2; HSS; MMCHD; MPMCD
Locus ID	2671
Cytogenetics	16p13.3
Summary	The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq, Jul 2008]

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