HCST (NM_001007469) Human Mass Spec Standard

Specifications

Product Data
Description	HCST MS Standard C13 and N15-labeled recombinant protein (NP_001007470)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC219253
Predicted MW	9.5 kDa
Protein Sequence	Sequence Link (showhide) >RC219253 protein sequence Red=Cloning site Green=Tags(s) MIHLGHILFLLLLPVAAAQTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVASLLIVGAVFL CARPRRSPAQEDGKVYINMPGRG TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001007470
RefSeq Size	521
RefSeq ORF	279
Synonyms	DAP10; KAP10; PIK3AP
Locus ID	10870
Cytogenetics	19q13.12
Summary	This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Natural killer cell mediated cytotoxicity

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.