FGF14 (NM_004115) Human Mass Spec Standard

Specifications

Product Data
Description	FGF14 MS Standard C13 and N15-labeled recombinant protein (NP_004106)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC219002
Predicted MW	27.5 kDa
Protein Sequence	Sequence Link (showhide) >RC219002 representing NM_004115 Red=Cloning site Green=Tags(s) MAAAIASGLIRQKRQAREQHWDRPSASRRRSSPSKNRGLCNGNLVDIFSKVRIFGLKKRRLRRQDPQLKG IVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFT PECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPS LHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_004106
RefSeq Size	890
RefSeq ORF	741
Synonyms	FGF-14; FHF-4; FHF4; SCA27
Locus ID	2259
Cytogenetics	13q33.1
Summary	The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families	Secreted Protein
Protein Pathways	MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

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