PDE5A (NM_033430) Human Mass Spec Standard
CAT#: PH318974
PDE5A MS Standard C13 and N15-labeled recombinant protein (NP_236914)
View other "PDE5A" proteins (5)
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CNY 19,520.00
Specifications
Product Data | |
Description | PDE5A MS Standard C13 and N15-labeled recombinant protein (NP_236914) |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC218974 |
Predicted MW | 94.6 kDa |
Protein Sequence |
>RC218974 representing NM_033430
Red=Cloning site Green=Tags(s) MLPFGDKTREMVNAWFAERVHTIPVCKEGIRGHTESCSCPLQQSPRADNSAPGTPTRKISASEFDRPLRP IVVKDSEGTVSFLSDSEKKEQMPLTPPRFDHDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISA DRYSLFLVCEDSSNDKFLISRLFDVAEGSTLEEVSNNCIRLEWNKGIVGHVAALGEPLNIKDAYEDPRFN AEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFCGIVLHNAQLYET SLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIFIVDEDCSDSFSSVFHMECEELE KSSDTLTREHDANKINYMYAQYVKNTMEPLNIPDVSKDKRFPWTTENTGNVNQQCIRSLLCTPIKNGKKN KVIGVCQLVNKMEENTGKVKPFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASA AEEETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSV KKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPL AQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKN QFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDLMNREKKNK IPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQQEKMLINGESGQAKRN TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
Reference Data | |
RefSeq | NP_236914 |
RefSeq Size | 6836 |
RefSeq ORF | 2499 |
Synonyms | CGB-PDE; CN5A; PDE5 |
Locus ID | 8654 |
Cytogenetics | 4q26 |
Summary | This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome |
Protein Pathways | Progesterone-mediated oocyte maturation, Purine metabolism |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC403251 | PDE5A HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
LC421205 | PDE5A HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
LY403251 | Transient overexpression lysate of phosphodiesterase 5A, cGMP-specific (PDE5A), transcript variant 2 |
CNY 4,840.00 |
|
LY421205 | Transient overexpression lysate of phosphodiesterase 5A, cGMP-specific (PDE5A), transcript variant 1 |
CNY 4,840.00 |
|
TP318974 | Recombinant protein of human phosphodiesterase 5A, cGMP-specific (PDE5A), transcript variant 2, 20 µg |
CNY 2,900.00 |