PDE5A (NM_033430) Human Mass Spec Standard

CAT#: PH318974

PDE5A MS Standard C13 and N15-labeled recombinant protein (NP_236914)



  View other "PDE5A" proteins (5)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of phosphodiesterase 5A, cGMP-specific (PDE5A), transcript variant 1
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Specifications

Product Data
Description PDE5A MS Standard C13 and N15-labeled recombinant protein (NP_236914)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC218974
Predicted MW 94.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_236914
RefSeq Size 6836
RefSeq ORF 2499
Synonyms CGB-PDE; CN5A; PDE5
Locus ID 8654
Cytogenetics 4q26
Summary This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Progesterone-mediated oocyte maturation, Purine metabolism
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