MAFF (NM_012323) Human Mass Spec Standard

Specifications

Product Data
Description	MAFF MS Standard C13 and N15-labeled recombinant protein (NP_036455)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC215609
Predicted MW	17.6 kDa
Protein Sequence	Sequence Link (showhide) >RC215609 representing NM_012323 Red=Cloning site Green=Tags(s) MSVDPLSSKALKIKRELSENTPHLSDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRTLKNRGYAASCRV KRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARSVAAARGPATLVAPASVITIV KSTPGSGSGPAHGPDPAHGPASCS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_036455
RefSeq Size	2382
RefSeq ORF	492
Synonyms	hMafF; U-MAF
Locus ID	23764
Cytogenetics	22q13.1
Summary	The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
Protein Families	Druggable Genome, Transcription Factors

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