MSRB2 (NM_012228) Human Mass Spec Standard

Specifications

Product Data
Description	MSRB2 MS Standard C13 and N15-labeled recombinant protein (NP_036360)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC215002
Predicted MW	21.47 kDa
Protein Sequence	Sequence Link (showhide) >RC215002 representing NM_012228 Red=Cloning site Green=Tags(s) MGAGAETGRGQRAAAPERRHGRLLWLLRGLTLGTAPRRAVRGQAGGGGPGTAGIVGEAGSLATCELPLAK SEWQKKLTPEQFYVTREKGTEPPFSGIYLNNKEAGMYHCVCCDSPLFSSEKKYCSGTGWPSFSEAHGTSG SDESHTGILRRLDTSLGSARTEVVCKQCEAHLGHVFPDGPGPNGQRFCINSVALKFKPRKH TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_036360
RefSeq Size	903
RefSeq ORF	603
Synonyms	CBS-1; CBS1; CGI-131; MSRB; PILB
Locus ID	22921
Cytogenetics	10p12.2
Summary	Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance.[UniProtKB/Swiss-Prot Function]
Protein Families	Transcription Factors

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