ARS2 (SRRT) (NM_015908) Human Mass Spec Standard

CAT#: PH314814

SRRT MS Standard C13 and N15-labeled recombinant protein (NP_056992)



  View other "ARS2" proteins (4)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of serrate RNA effector molecule homolog (Arabidopsis) (SRRT), transcript variant 1
    • 100 ug

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Goat Polyclonal Anti-SRRT / ARS2 Antibody
    • 100 ug

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Specifications

Product Data
Description SRRT MS Standard C13 and N15-labeled recombinant protein (NP_056992)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC214814
Predicted MW 100.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_056992
RefSeq Size 2994
RefSeq ORF 2628
Synonyms ARS2; ASR2; serrate
Locus ID 51593
Cytogenetics 7q22.1
Summary Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).[UniProtKB/Swiss-Prot Function]
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