STAR (NM_001007243) Human Mass Spec Standard

CAT#: PH313299

STAR MS Standard C13 and N15-labeled recombinant protein (NP_001007244)



  View other "STAR" proteins (9)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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经常一起买 (2)
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Specifications

Product Data
Description STAR MS Standard C13 and N15-labeled recombinant protein (NP_001007244)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC213299
Predicted MW 29.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001007244
RefSeq Size 2641
RefSeq ORF 801
Synonyms cholesterol trafficker; mitochondrial steroid acute regulatory protein; StAR-related lipid transfer (START) domain containing 1; STARD1; START domain containing 1; steroid acute regulatory protein; steroidogenic acute regula; steroidogenic acute regulator
Locus ID 6770
Cytogenetics 8p11.23
Summary The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
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