FAM195B (MCRIP1) (NM_207368) Human Mass Spec Standard

CAT#: PH311513

FAM195B MS Standard C13 and N15-labeled recombinant protein (NP_997251)



  View other "FAM195B" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (1)
Transient overexpression lysate of family with sequence similarity 195, member B (FAM195B), transcript variant 1
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Description FAM195B MS Standard C13 and N15-labeled recombinant protein (NP_997251)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC211513
Predicted MW 10.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_997251
RefSeq Size 2980
RefSeq ORF 525
Synonyms FAM195B; GRAN2; MCRIP
Locus ID 348262
Cytogenetics 17q25.3
Summary The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition. Unphosphorylated MCRIP1 binds to and inhibits the transcriptional corepressor CTBP(s). When phosphorylated by MAPK/ERK, MCRIP1 releases CTBP(s) resulting in transcriptional silencing of the E-cadherin gene and induction of epithelial-mesenchymal transition (PubMed:25728771).[UniProtKB/Swiss-Prot Function]
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