PGRPS (PGLYRP1) (NM_005091) Human Mass Spec Standard

Specifications

Product Data
Description	PGLYRP1 MS Standard C13 and N15-labeled recombinant protein (NP_005082)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC211040
Predicted MW	21.7 kDa
Protein Sequence	Sequence Link (showhide) >RC211040 protein sequence Red=Cloning site Green=Tags(s) MSRRSMLLAWALPSLLRLGAAQETEDPACCSPIVPRNEWKALASECAQHLSLPLRYVVVSHTAGSSCNTP ASCQQQARNVQHYHMKTLGWCDVGYNFLIGEDGLVYEGRGWNFTGAHSGHLWNPMSIGISFMGNYMDRVP TPQAIRAAQGLLACGVAQGALRSNYVLKGHRDVQRTLSPGNQLYHLIQNWPHYRSP TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_005082
RefSeq Size	972
RefSeq ORF	588
Synonyms	PGLYRP; PGRP; PGRP-S; PGRPS; TAG7; TNFSF3L
Locus ID	8993
Cytogenetics	19q13.32
Summary	Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.[UniProtKB/Swiss-Prot Function]
Protein Families	Druggable Genome, Secreted Protein

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