Nkx3.1 (NKX3-1) (NM_006167) Human Mass Spec Standard

Specifications

Product Data
Description	NKX3 MS Standard C13 and N15-labeled recombinant protein (NP_006158)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC210374
Predicted MW	26.4 kDa
Protein Sequence	Sequence Link (showhide) >RC210374 protein sequence Red=Cloning site Green=Tags(s) MLRVPEPRPGEAKAEGAAPPTPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEPEPEGGRSRAG AQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELE RKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGDLEKHSSLPALKEEAFSRASL VSVYNSYPYYPYLYCVGSWSPAFW TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006158
RefSeq Size	3281
RefSeq ORF	702
Synonyms	BAPX2; NKX3; NKX3.1; NKX3A
Locus ID	4824
Cytogenetics	8p21.2
Summary	This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jan 2012]
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Pathways in cancer, Prostate cancer

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