KCNJ5 (NM_000890) Human Mass Spec Standard

Specifications

Product Data
Description	KCNJ5 MS Standard C13 and N15-labeled recombinant protein (NP_000881)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC210184
Predicted MW	47.7 kDa
Protein Sequence	Sequence Link (showhide) >Peptide sequence encoded by RC210184 Blue=ORF Red=Cloning site Green=Tag(s) MAGDSRNAMNQDMEIGVTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKCNVHHGNVQE TYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVS AFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAV ISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLII SHEINEKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYE VDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSRE ARGSV TRTRPLEQKLISEEDLAANDILDYKDDDDKV Recombinant protein using RC210184 also available, TP310184
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_000881
RefSeq Size	2912
RefSeq ORF	1257
Synonyms	CIR; GIRK4; KATP1; KIR3.4; LQT13
Locus ID	3762
Cytogenetics	11q24.3
Summary	This gene encodes an integral membrane protein which belongs to one of seven subfamilies of inward-rectifier potassium channel proteins called potassium channel subfamily J. The encoded protein is a subunit of the potassium channel which is homotetrameric. It is controlled by G-proteins and has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Naturally occurring mutations in this gene are associated with aldosterone-producing adenomas. [provided by RefSeq, Aug 2017]
Protein Families	Druggable Genome, Ion Channels: Potassium, Transmembrane

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