C13orf15 (RGCC) (NM_014059) Human Mass Spec Standard

Specifications

Product Data
Description	C13orf15 MS Standard C13 and N15-labeled recombinant protein (NP_054778)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC209810
Predicted MW	14.6 kDa
Protein Sequence	Sequence Link (showhide) >RC209810 protein sequence Red=Cloning site Green=Tags(s) MKQPAAQGSPAAAAAAAPALDSAAAEDLSDALCEFDAVLADFASPFHERHFHYEEHLERMKRRSSASVSD SSGFSDSESADSLYRNSFSFSDEKLNSPTDSTPALLSATVTPQKAKLGDTKELEAFIADLDKTLASM TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_054778
RefSeq Size	1126
RefSeq ORF	411
Synonyms	bA157L14.2; C13orf15; RGC-32; RGC32
Locus ID	28984
Cytogenetics	13q14.11
Summary	This gene is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression. [provided by RefSeq, Jul 2008]

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