CGGBP1 (NM_003663) Human Mass Spec Standard

CAT#: PH308653

CGGBP1 MS Standard C13 and N15-labeled recombinant protein (NP_003654)



  View other "CGGBP1" proteins (7)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description CGGBP1 MS Standard C13 and N15-labeled recombinant protein (NP_003654)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC208653
Predicted MW 18.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_003654
RefSeq Size 4506
RefSeq ORF 501
Synonyms CGGBP; p20-CGGBP
Locus ID 8545
Cytogenetics 3p11.1
Summary This gene encodes a CGG repeat-binding protein that primarily localizes to the nucleus. CGG trinucleotide repeats are implicated in many disorders as they often act as transcription- and translation-regulatory elements, can produce hairpin structures which cause DNA replication errors, and form regions prone to chromosomal breakage. CGG repeats are also targets for CpG methylation. In addition to its ability to bind CGG repeats and regulate transcription, this gene is believed to play a role in DNA damage repair and telomere protection. In vitro studies indicate this protein does not bind to methylated CpG sequences. [provided by RefSeq, Jul 2017]
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