GRB10 (NM_001001555) Human Mass Spec Standard

CAT#: PH306853

GRB10 MS Standard C13 and N15-labeled recombinant protein (NP_001001555)



  View other "GRB10" proteins (11)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description GRB10 MS Standard C13 and N15-labeled recombinant protein (NP_001001555)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC206853
Predicted MW 60.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001001555
RefSeq Size 5040
RefSeq ORF 1608
Synonyms Grb-10; GRB-IR; IRBP; MEG1; RSS
Locus ID 2887
Cytogenetics 7p12.1
Summary The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]
Protein Families Druggable Genome
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