IDO1 (NM_002164) Human Mass Spec Standard

CAT#: PH306592

IDO1 MS Standard C13 and N15-labeled recombinant protein (NP_002155)



  View other "IDO1" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of indoleamine 2,3-dioxygenase 1 (IDO1)
    • 100 ug

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IDO1 mouse monoclonal antibody, clone OTI1A3 (formerly 1A3)
    • 100 ul

CNY 1,999.00
CNY 2,700.00

Specifications

Product Data
Description IDO1 MS Standard C13 and N15-labeled recombinant protein (NP_002155)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC206592
Predicted MW 45.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_002155
RefSeq Size 1944
RefSeq ORF 1209
Synonyms IDO; IDO-1; INDO
Locus ID 3620
Cytogenetics 8p11.21
Summary This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Tryptophan metabolism
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