IDO1 (NM_002164) Human Mass Spec Standard
CAT#: PH306592
IDO1 MS Standard C13 and N15-labeled recombinant protein (NP_002155)
View other "IDO1" proteins (3)
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CNY 19,520.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Description | IDO1 MS Standard C13 and N15-labeled recombinant protein (NP_002155) |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC206592 |
Predicted MW | 45.3 kDa |
Protein Sequence |
>RC206592 protein sequence
Red=Cloning site Green=Tags(s) MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHL TDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPN KPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKA LQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQ QTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIV TKYILIPASQQPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
Reference Data | |
RefSeq | NP_002155 |
RefSeq Size | 1944 |
RefSeq ORF | 1209 |
Synonyms | IDO; IDO-1; INDO |
Locus ID | 3620 |
Cytogenetics | 8p11.21 |
Summary | This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011] |
Protein Families | Druggable Genome |
Protein Pathways | Metabolic pathways, Tryptophan metabolism |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400784 | IDO1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY400784 | Transient overexpression lysate of indoleamine 2,3-dioxygenase 1 (IDO1) |
CNY 3,080.00 |
|
TP306592 | Recombinant protein of human indoleamine 2,3-dioxygenase 1 (IDO1), 20 µg |
CNY 2,900.00 |