FN3K (NM_022158) Human Mass Spec Standard

Specifications

Product Data
Description	FN3K MS Standard C13 and N15-labeled recombinant protein (NP_071441)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC206432
Predicted MW	35.2 kDa
Protein Sequence	Sequence Link (showhide) >RC206432 protein sequence Red=Cloning site Green=Tags(s) MEQLLRAELRTATLRAFGGPGAGCISEGRAYDTDAGPVFVKVNRRTQARQMFEGEVASLEALRSTGLVRV PRPMKVIDLPGGGAAFVMEHLKMKSLSSQASKLGEQMADLHLYNQKLREKLKEEENTVGRRGEGAEPQYV DKFGFHTVTCCGFIPQVNEWQDDWPTFFARHRLQAQLDLIEKDYADREARELWSRLQVKIPDLFCGLEIV PALLHGDLWSGNVAEDDVGPIIYDPASFYGHSEFELAIALMFGGFPRSFFTAYHRKIPKAPGFDQRLLLY QLFNYLNHWNHFGREYRSPSLGTMRRLLK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_071441
RefSeq Size	1433
RefSeq ORF	927
Locus ID	64122
Cytogenetics	17q25.3
Summary	A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation. [provided by RefSeq, Feb 2012]
Protein Families	Druggable Genome

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