STAC (NM_003149) Human Mass Spec Standard

Specifications

Product Data
Description	STAC MS Standard C13 and N15-labeled recombinant protein (NP_003140)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC205851
Predicted MW	44.6 kDa
Protein Sequence	Sequence Link (showhide) >RC205851 protein sequence Red=Cloning site Green=Tags(s) MIPPSSPREDGVDGLPKEAVGAEQPPSPASTSSQESKLQKLKRSLSFKTKSLRSKSADNFFQRTNSEDMK LQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFHEYIFKKPTFCDVCNHMIVGTNAKHGLRCK ACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLA QRTKKGSSGSGSDSPHRTSTSDLVEVPEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSL SKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFR CVRTFIGCKEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_003140
RefSeq Size	3098
RefSeq ORF	1206
Synonyms	STAC1
Locus ID	6769
Cytogenetics	3p22.3-p22.2
Summary	Promotes expression of the ion channel CACNA1H at the cell membrane, and thereby contributes to the regulation of channel activity. Plays a minor and redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel activity. Slows down the inactivation rate of the calcium channel CACNA1C.[UniProtKB/Swiss-Prot Function]

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