splicing factor 1 (SF1) (NM_201998) Human Mass Spec Standard

CAT#: PH305846

SF1 MS Standard C13 and N15-labeled recombinant protein (NP_973727)



  View other "splicing factor 1" proteins (9)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description SF1 MS Standard C13 and N15-labeled recombinant protein (NP_973727)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC205846
Predicted MW 59.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_973727
RefSeq Size 2949
RefSeq ORF 1644
Synonyms BBP; D11S636; MBBP; ZCCHC25; ZFM1; ZNF162
Locus ID 7536
Cytogenetics 11q13.1
Summary This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Protein Families Transcription Factors
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