Asialoglycoprotein Receptor 1 (ASGR1) (NM_001671) Human Mass Spec Standard

CAT#: PH305686

ASGR1 MS Standard C13 and N15-labeled recombinant protein (NP_001662)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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Specifications

Product Data
Description ASGR1 MS Standard C13 and N15-labeled recombinant protein (NP_001662)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC205686
Predicted MW 33.2 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001662
RefSeq Size 1519
RefSeq ORF 873
Synonyms ASGPR; ASGPR1; CLEC4H1; HL-1
Locus ID 432
Cytogenetics 17p13.1
Summary This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Protein Families Druggable Genome, Transmembrane
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