CPLX3 (NM_001030005) Human Mass Spec Standard

Specifications

Product Data
Description	CPLX3 MS Standard C13 and N15-labeled recombinant protein (NP_001025176)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC205172
Predicted MW	17.6 kDa
Protein Sequence	Sequence Link (showhide) >RC205172 protein sequence Red=Cloning site Green=Tags(s) MAFMVKTMVGGQLKNLTGSLGGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQRKAERA TLRSHFRDKYRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEKASVLGQLASLPGLNLGSLKDK AQATLGDLKQSAEKCHVM TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001025176
RefSeq Size	2012
RefSeq ORF	474
Synonyms	CPX-III; CPXIII; Nbla11589
Locus ID	594855
Cytogenetics	15q24.1
Summary	Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion (By similarity). Required for the maintenance of synaptic ultrastructure in the adult retina (By similarity). Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina (By similarity). Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release (By similarity).[UniProtKB/Swiss-Prot Function]

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