HSPC014 (POMP) (NM_015932) Human Mass Spec Standard

Specifications

Product Data
Description	POMP MS Standard C13 and N15-labeled recombinant protein (NP_057016)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204812
Predicted MW	15.8 kDa
Protein Sequence	Sequence Link (showhide) >RC204812 protein sequence Red=Cloning site Green=Tags(s) MNARGLGSELKDSIPVTELSASGPFESHDLLRKGFSCVKNELLPSHPLELSEKNFQLNQDKMNFSTLRNI QGLFAPLKLQMEFKAVQQVQRLPFLSSSNLSLDVLRGNDETIGFEDILNDPSQSEVMGEPHLMVEYKLGL L TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_057016
RefSeq Size	1477
RefSeq ORF	423
Synonyms	C13orf12; HSPC014; PNAS-110; PRAAS2; UMP1
Locus ID	51371
Cytogenetics	13q12.3
Summary	The protein encoded by this gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder.[provided by RefSeq, Aug 2010]
Protein Pathways	Proteasome

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