NIP30 (FAM192A) (NM_024946) Human Mass Spec Standard

Specifications

Product Data
Description	FAM192A MS Standard C13 and N15-labeled recombinant protein (NP_079222)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204378
Predicted MW	28.9 kDa
Protein Sequence	Sequence Link (showhide) >RC204378 protein sequence Red=Cloning site Green=Tags(s) MDGGDDGNLIIKKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYE EQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKLTVKP IETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQEPSSCKSLGNTSLSGPSIHCPSAAVCIG ILPGLGAYSGSSDSESSSDSEGTINATGKIVSSIFRTNTFLEAP TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_079222
RefSeq Size	2865
RefSeq ORF	762
Synonyms	C16orf94; CDA018; CDA10; FAM192A; NIP30; PIP30
Locus ID	80011
Cytogenetics	16q13
Summary	Promotes the association of the proteasome activator complex subunit PSME3 with the 20S proteasome and regulates its activity. Inhibits PSME3-mediated degradation of some proteasome substrates, probably by affecting their diffusion rate into the catalytic chamber of the proteasome. Also inhibits the interaction of PSME3 with COIL, inhibits accumulation of PSME3 in Cajal bodies and positively regulates the number of Cajal bodies in the nucleus.[UniProtKB/Swiss-Prot Function]

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