SSX2 (NM_175698) Human Mass Spec Standard

CAT#: PH303504

SSX2 MS Standard C13 and N15-labeled recombinant protein (NP_783629)



  View other "SSX2" proteins (7)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description SSX2 MS Standard C13 and N15-labeled recombinant protein (NP_783629)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203504
Predicted MW 21.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_783629
RefSeq Size 1348
RefSeq ORF 564
Synonyms CT5.2; CT5.2A; HD21; HOM-MEL-40; SSX
Locus ID 6757
Cytogenetics Xp11.22
Summary The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X. [provided by RefSeq, Jul 2013]
Protein Families Druggable Genome, Transcription Factors
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