Cyclophilin B (PPIB) (NM_000942) Human Mass Spec Standard

Specifications

Product Data
Description	PPIB MS Standard C13 and N15-labeled recombinant protein (NP_000933)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203180
Predicted MW	23.7 kDa
Protein Sequence	Sequence Link (showhide) >RC203180 protein sequence Red=Cloning site Green=Tags(s) MLRLSERNMKVLLAAALIAGSVFFLLLPGPSAADEKKKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVP KTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSM ANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCGKIEVEKP FAIAKE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_000933
RefSeq Size	1045
RefSeq ORF	648
Synonyms	B; CYP-S1; CYPB; HEL-S-39; OI9; SCYLP
Locus ID	5479
Cytogenetics	15q22.31
Summary	The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]
Protein Families	Druggable Genome, Transmembrane

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