ISG20 (NM_002201) Human Mass Spec Standard

Specifications

Product Data
Description	ISG20 MS Standard C13 and N15-labeled recombinant protein (NP_002192)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203178
Predicted MW	20.4 kDa
Protein Sequence	Sequence Link (showhide) >RC203178 protein sequence Red=Cloning site Green=Tags(s) MAGSREVVAMDCEMVGLGPHRESGLARCSLVNVHGAVLYDKFIRPEGEITDYRTRVSGVTPQHMVGATPF AVARLEILQLLKGKLVVGHDLKHDFQALKEDMSGYTIYDTSTDRLLWREAKLDHCRRVSLRVLSERLLHK SIQNSLLGHSSVEDARATMELYQISQRIRARRGLPRLAVSD TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002192
RefSeq Size	974
RefSeq ORF	543
Synonyms	CD25; HEM45
Locus ID	3669
Cytogenetics	15q26.1
Summary	Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis.[UniProtKB/Swiss-Prot Function]

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