Myosin light chain 3 (MYL3) (NM_000258) Human Mass Spec Standard

Specifications

Product Data
Description	MYL3 MS Standard C13 and N15-labeled recombinant protein (NP_000249)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203122
Predicted MW	21.9 kDa
Protein Sequence	Sequence Link (showhide) >RC203122 protein sequence Red=Cloning site Green=Tags(s) MAPKKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMK ITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVF DKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMSS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_000249
RefSeq Size	942
RefSeq ORF	585
Synonyms	CMH8; MLC-lV/sb; MLC1SB; MLC1V; VLC1; VLCl
Locus ID	4634
Cytogenetics	3p21.31
Summary	MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome
Protein Pathways	Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

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