ZDH12 (ZDHHC12) (NM_032799) Human Mass Spec Standard

Specifications

Product Data
Description	ZDHHC12 MS Standard C13 and N15-labeled recombinant protein (NP_116188)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203011
Predicted MW	30.6 kDa
Protein Sequence	Sequence Link (showhide) >RC203011 representing NM_032799 Red=Cloning site Green=Tags(s) MAPWALLSPGVLVRTGHTVLTWGITLVLFLHDTELRQWEEQGELLLPLTFLLLVLGSLLLYLAVSLMDPG YVNVQPQPQEELKEEQTAMVPPAIPLRRCRYCLVLQPLRARHCRECRRCVRRYDHHCPWMENCVGERNHP LFVVYLALQLVVLLWGLYLAWSGLRFFQPWGLWLRSSGLLFATFLLLSLFSLVASLLLVSHLYLVASNTT TWEFISSHRIAYLRQRPSNPFDRGLTRNLAHFFCGWPSGSWETLWAEEEEEGSSPAV TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_116188
RefSeq Size	1184
RefSeq ORF	801
Synonyms	DHHC-12; ZNF400
Locus ID	84885
Cytogenetics	9q34.11
Summary	Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates. Has a palmitoyltransferase activity toward gephyrin/GPHN, regulating its clustering at synapses and its function in gamma-aminobutyric acid receptor clustering. Thereby, indirectly regulates GABAergic synaptic transmission.[UniProtKB/Swiss-Prot Function]
Protein Families	Transmembrane

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