Frequenin (NCS1) (NM_014286) Human Mass Spec Standard

Specifications

Product Data
Description	NCS1 MS Standard C13 and N15-labeled recombinant protein (NP_055101)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202389
Predicted MW	21.9 kDa
Protein Sequence	Sequence Link (showhide) >RC202389 protein sequence Red=Cloning site Green=Tags(s) MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFN VFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVELPE EENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_055101
RefSeq Size	5009
RefSeq ORF	570
Synonyms	FLUP; FREQ
Locus ID	23413
Cytogenetics	9q34.11
Summary	This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome

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