ILF2 (NM_004515) Human Mass Spec Standard

CAT#: PH301751

ILF2 MS Standard C13 and N15-labeled recombinant protein (NP_004506)



  View other "ILF2" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of interleukin enhancer binding factor 2, 45kDa (ILF2)
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Anti-ILF2 mouse monoclonal antibody, clone OTI6F1 (formerly 6F1)
    • 100 ul

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Specifications

Product Data
Description ILF2 MS Standard C13 and N15-labeled recombinant protein (NP_004506)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201751
Predicted MW 43.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_004506
RefSeq Size 1934
RefSeq ORF 1170
Synonyms NF45; PRO3063
Locus ID 3608
Cytogenetics 1q21.3
Summary The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. [provided by RefSeq, Dec 2014]
Protein Families Druggable Genome, Transcription Factors
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