Proteasome 20S beta 6 (PSMB6) (NM_002798) Human Mass Spec Standard

Specifications

Product Data
Description	PSMB6 MS Standard C13 and N15-labeled recombinant protein (NP_002789)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC201605
Predicted MW	25.4 kDa
Protein Sequence	Sequence Link (showhide) >RC201605 protein sequence Red=Cloning site Green=Tags(s) MAATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTP IHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQ EGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRL AAIAESGVERQVLLGDQIPKFAVATLPPA TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002789
RefSeq Size	869
RefSeq ORF	717
Synonyms	DELTA; LMPY; Y
Locus ID	5694
Cytogenetics	17p13.2
Summary	The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Protein Families	Druggable Genome, Protease
Protein Pathways	Proteasome

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