VPS29 (NM_057180) Human Mass Spec Standard

Specifications

Product Data
Description	VPS29 MS Standard C13 and N15-labeled recombinant protein (NP_476528)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC201460
Predicted MW	20.9 kDa
Protein Sequence	Sequence Link (showhide) >RC201460 protein sequence Red=Cloning site Green=Tags(s) MAGHRLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDEN LNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSAT GAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKP TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_476528
RefSeq Size	1153
RefSeq ORF	558
Synonyms	DC7; DC15; PEP11
Locus ID	51699
Cytogenetics	12q24.11
Summary	This gene belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein encoded by this gene is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. This VPS protein may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different isoforms and representing non-protein coding transcripts have been found for this gene. [provided by RefSeq, Aug 2013]

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