Flavin containing monooxygenase 4 (FMO4) (NM_002022) Human Mass Spec Standard

CAT#: PH301181

FMO4 MS Standard C13 and N15-labeled recombinant protein (NP_002013)



  View other "Flavin containing monooxygenase 4" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of flavin containing monooxygenase 4 (FMO4)
    • 100 ug

CNY 3,080.00


FMO4 Antibody - N-terminal region
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Description FMO4 MS Standard C13 and N15-labeled recombinant protein (NP_002013)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201181
Predicted MW 63.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_002013
RefSeq Size 2148
RefSeq ORF 1674
Synonyms FMO2
Locus ID 2329
Cytogenetics 1q24.3
Summary Metabolic N-oxidation of diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man. This results in a small subpopulation with reduced TMA N-oxidation capacity and causes fish odor syndrome (Trimethylaminuria). Three forms of the enzyme are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. [provided by RefSeq, Jan 2015]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Drug metabolism - cytochrome P450
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