RNF181 (NM_016494) Human Mass Spec Standard

Specifications

Product Data
Description	RNF181 MS Standard C13 and N15-labeled recombinant protein (NP_057578)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC201048
Predicted MW	17.9 kDa
Protein Sequence	Sequence Link (showhide) >RC201048 protein sequence Red=Cloning site Green=Tags(s) MASYFDEHDCEPSDPEQETRTNMLLELARSLFNRMDFEDLGLVVDWDHHLPPPAAKTVVENLPRTVIRGS QAELKCPVCLLEFEEEETAIEMPCHHLFHSSCILPWLSKTNSCPLCRYELPTDDDTYEEHRRDKARKQQQ QHRLENLHGAMYT TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_057578
RefSeq Size	716
RefSeq ORF	459
Synonyms	HSPC238
Locus ID	51255
Cytogenetics	2p11.2
Summary	RNF181 binds the integrin alpha-IIb (ITGA2B; MIM 607759)/beta-3 (ITGB3; MIM 173470) complex and has E3 ubiquitin ligase activity (Brophy et al., 2008 [PubMed 18331836]).[supplied by OMIM, Dec 2008]
Protein Families	Druggable Genome

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