HYPK (NM_016400) Human Mass Spec Standard

Specifications

Product Data
Description	C15orf63 MS Standard C13 and N15-labeled recombinant protein (NP_057484)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200840
Predicted MW	14.7 kDa
Protein Sequence	Sequence Link (showhide) >RC200840 protein sequence Red=Cloning site Green=Tags(s) MRRRGEIDMATEGDVELELETETSGPERPPEKPRKHDSGAADLERVTDYAEEKEIQSSNLETAMSVIGDR RSREQKAKQEREKELAKVTIKKEDLELIMTEMEISRAAAERSLREHMGNVVEALIALTN TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_057484
RefSeq Size	1351
RefSeq ORF	387
Synonyms	C15orf63; HSPC136
Locus ID	25764
Cytogenetics	15q15.3
Summary	Has a chaperone-like activity preventing polyglutamine (polyQ) aggregation of HTT. Protects against HTT polyQ-mediated apoptosis in Neuro2a neuronal cells. Required for optimal NAA10-NAA15 complex-mediated N-terminal acetylation.[UniProtKB/Swiss-Prot Function]

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