Lysozyme (LYZ) (NM_000239) Human Mass Spec Standard

Specifications

Product Data
Description	LYZ MS Standard C13 and N15-labeled recombinant protein (NP_000230)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200730
Predicted MW	16.5 kDa
Protein Sequence	Sequence Link (showhide) >RC200730 protein sequence Red=Cloning site Green=Tags(s) MKALIVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRST DYGIFQINSRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVR QYVQGCGV TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_000230
RefSeq Size	1516
RefSeq ORF	444
Synonyms	LYZF1; LZM
Locus ID	4069
Cytogenetics	12q15
Summary	This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species. Missense mutations in this gene have been identified in heritable renal amyloidosis. [provided by RefSeq, Oct 2014]
Protein Families	Druggable Genome

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