MTHFD1 (NM_005956) Human Mass Spec Standard

CAT#: PH300297

MTHFD1 MS Standard C13 and N15-labeled recombinant protein (NP_005947)



  View other "MTHFD1" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase (MTHFD1)
    • 100 ug

CNY 3,080.00


Rabbit Polyclonal Anti-MTHFD1 Antibody
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Description MTHFD1 MS Standard C13 and N15-labeled recombinant protein (NP_005947)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200297
Predicted MW 101.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_005947
RefSeq Size 3466
RefSeq ORF 2805
Synonyms CIMAH; MTHFC; MTHFD
Locus ID 4522
Cytogenetics 14q23.3
Summary This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Glyoxylate and dicarboxylate metabolism, Metabolic pathways, One carbon pool by folate
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