C9orf95 (NMRK1) (NM_017881) Human Mass Spec Standard

Specifications

Product Data
Description	C9orf95 MS Standard C13 and N15-labeled recombinant protein (NP_060351)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200160
Predicted MW	23.2 kDa
Protein Sequence	Sequence Link (showhide) >RC200160 protein sequence Red=Cloning site Green=Tags(s) MKTFIIGISGVTNSGKTTLAKNLQKHLPNCSVISQDDFFKPESEIETDKNGFLQYDVLEALNMEKMMSAI SCWMESARHSVVSTDQESAEEIPILIIEGFLLFNYKPLDTIWNRSYFLTIPYEECKRRRSTRVYQPPDSP GYFDGHVWPMYLKYRQEMQDITWEVVYLDGTKSEEDLFLQVYEDLIQELAKQKCLQVTA TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_060351
RefSeq Size	1207
RefSeq ORF	597
Synonyms	bA235O14.2; C9orf95; NRK1
Locus ID	54981
Cytogenetics	9q21.13
Summary	Nicotinamide adenine dinucleotide (NAD+) is essential for life in all organisms, both as a coenzyme for oxidoreductases and as a source of ADP-ribosyl groups used in various reactions. Nicotinic acid and nicotinamide, collectively known as niacin, are the vitamin precursors of NAD+. Nicotinamide riboside kinases, such as NRK1, function to synthesize NAD+ through nicotinamide mononucleotide using nicotinamide riboside as the precursor (Bieganowski and Brenner, 2004 [PubMed 15137942]).[supplied by OMIM, Mar 2008]
Protein Pathways	Nicotinate and nicotinamide metabolism

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