Human EMSY activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EMSY
Locus ID	56946
Kit Components	GA111292G1, EMSY gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111292G2, EMSY gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111292G3, EMSY gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001300942, NM_001300943, NM_001300944, NM_020193
Synonyms	C11orf30; GL002
Summary	Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors.[UniProtKB/Swiss-Prot Function]

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