Human Aquaporin 7 (AQP7) activation kit by CRISPRa
CAT#: GA100261
AQP7 CRISPRa kit - CRISPR gene activation of human aquaporin 7
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | AQP7 |
Locus ID | 364 |
Kit Components | GA100261G1, Aquaporin 7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100261G2, Aquaporin 7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100261G3, Aquaporin 7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001170, NM_001318156, NM_001318157, NM_001318158, NR_134513, NR_134514, NR_134515 |
Synonyms | AQP7L; AQP9; AQPap; GLYCQTL |
Summary | This gene encodes a member of the aquaporin family of water-selective membrane channels. The encoded protein localizes to the plasma membrane and allows movement of water, glycerol and urea across cell membranes. This gene is highly expressed in the adipose tissue where the encoded protein facilitates efflux of glycerol. In the proximal straight tubules of kidney, the encoded protein is localized to the apical membrane and prevents excretion of glycerol into urine. The encoded protein is present in spermatids, as well as in the testicular and epididymal spermatozoa suggesting an important role in late spermatogenesis. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. This gene is located adjacent to a related aquaporin gene on chromosome 9. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Dec 2015] |
Documents
Resources
基因表达相关资源 |
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