Zdhhc3 (NM_001039014) Rat Tagged ORF Clone Lentiviral Particle

CAT#: RR214516L3V

  • LentiORF®

Lenti ORF particles, Zdhhc3 (Myc-DDK-tagged ORF) - Rat zinc finger, DHHC-type containing 3 (Zdhhc3), 200ul, >10^7 TU/mL



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CNY 7,410.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Zdhhc3 (NM_001039014) Rat Tagged ORF Clone Lentiviral Particle
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_001039014
ORF Size 897 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RR214516).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001039014.1, NP_001034103.1
RefSeq Size 1880 bp
RefSeq ORF 900 bp
Locus ID 301081
Gene Summary Golgi-localized palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates. Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA (By similarity). Plays an important role in G protein-coupled receptor signaling pathways involving GNAQ and potentially other heterotrimeric G proteins by regulating their dynamic association with the plasma membrane (By similarity). Palmitoylates ITGA6 and ITGB4, thereby regulating the alpha-6/beta-4 integrin localization, expression and function in cell adhesion to laminin (By similarity). Plays a role in the TRAIL-activated apoptotic signaling pathway most probably through the palmitoylation and localization to the plasma membrane of TNFRSF10A (By similarity). In the brain, by palmitoylating the gamma subunit GABRG2 of GABA(A) receptors and regulating their postsynaptic accumulation, plays a role in synaptic GABAergic inhibitory function and GABAergic innervation. Palmitoylates the neuronal protein GAP43 which is also involved in the formation of GABAergic synapses. Palmitoylates NCDN thereby regulating its association with endosome membranes. Probably palmitoylates PRCD and is involved in its proper localization within the photoreceptor. Could mediate the palmitoylation of NCAM1 and regulate neurite outgrowth. Could palmitoylate DNAJC5 and regulate its localization to Golgi membranes (By similarity). Also constitutively palmitoylates DLG4 (PubMed:19596852). May also palmitoylate SNAP25. Could palmitoylate the glutamate receptors GRIA1 and GRIA2 but this has not been confirmed in vivo (By similarity). Could also palmitoylate the D(2) dopamine receptor DRD2.[UniProtKB/Swiss-Prot Function]
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