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Psenen (NM_001008764) Rat Tagged ORF Clone Lentiviral Particle
CAT＃: RR210155L3V
- LentiORF®
-
Lenti ORF particles, Psenen (Myc-DDK-tagged ORF) - Rat presenilin enhancer 2 homolog (C. elegans) (Psenen), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Psenen (NM_001008764) Rat Tagged ORF Clone Lentiviral Particle |
| Synonyms | RGD1312037 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001008764 |
| ORF Size | 303 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RR210155).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001008764.2, NP_001008764.1 |
| RefSeq Size | 572 bp |
| RefSeq ORF | 306 bp |
| Locus ID | 292788 |
| Gene Summary | Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. PSENEN modulates both endoproteolysis of presenilin and gamma-secretase activity.[UniProtKB/Swiss-Prot Function] |
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