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Creb3l2 (NM_001012188) Rat Tagged ORF Clone Lentiviral Particle
CAT＃: RR208758L4V
- LentiORF®
-
Lenti ORF particles, Creb3l2 (GFP-tagged ORF) - Rat cAMP responsive element binding protein 3-like 2 (Creb3l2), 200ul, >10^7 TU/mL
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CNY 10,925.00
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Specifications
| Product Data | |
| Product Name | Creb3l2 (NM_001012188) Rat Tagged ORF Clone Lentiviral Particle |
| Synonyms | Ra69; SCIRR69 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001012188 |
| ORF Size | 1563 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RR208758).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001012188.1, NP_001012188.1 |
| RefSeq Size | 3321 bp |
| RefSeq ORF | 1566 bp |
| Locus ID | 362339 |
| Gene Summary | Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis by activating the transcription of SEC23A, which promotes the transport and secretion of cartilage matrix proteins, and possibly that of ER biogenesis-related genes. In a neuroblastoma cell line, protects cells from ER stress-induced death. In vitro activates transcription of target genes via direct binding to the CRE site.[UniProtKB/Swiss-Prot Function] |
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