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MDH1 (NM_001199112) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC230787L3V
- LentiORF®
-
Lenti ORF particles, MDH1 (Myc-DDK-tagged)-Human malate dehydrogenase 1, NAD (soluble) (MDH1), transcript variant 3, 200ul, >10^7 TU/mL
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CNY 7,410.00
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规格
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Specifications
| Product Data | |
| Product Name | MDH1 (NM_001199112) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | DEE88; EIEE88; HEL-S-32; KAR; MDH-s; MDHA; MGC:1375; MOR2 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001199112 |
| ORF Size | 1005 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC230787).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001199112.1, NP_001186041.1 |
| RefSeq Size | 1364 bp |
| RefSeq ORF | 738 bp |
| Locus ID | 4190 |
| Protein Families | Druggable Genome |
| Protein Pathways | Citrate cycle (TCA cycle), Glyoxylate and dicarboxylate metabolism, Metabolic pathways, Pyruvate metabolism |
| MW | 36.4 kDa |
| Gene Summary | This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6. [provided by RefSeq, Feb 2016] |
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