RNF170 (NM_001160224) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC228756L3V
- LentiORF®
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Lenti ORF particles, RNF170 (Myc-DDK-tagged)-Human ring finger protein 170 (RNF170), transcript variant 3, 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | RNF170 (NM_001160224) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | ADSA; SNAX1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001160224 |
ORF Size | 600 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC228756).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001160224.1 |
RefSeq ORF | 603 bp |
Locus ID | 81790 |
Protein Families | Druggable Genome, Transmembrane |
MW | 22 kDa |
Gene Summary | This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012] |
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