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OTUD5 (NM_001136157) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC227573L3V
- LentiORF®
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Lenti ORF particles, OTUD5 (Myc-DDK tagged) - Human OTU domain containing 5 (OTUD5), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 10,260.00
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Specifications
| Product Data | |
| Product Name | OTUD5 (NM_001136157) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | DUBA; MCAND |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001136157 |
| ORF Size | 1698 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC227573).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001136157.1 |
| RefSeq ORF | 1701 bp |
| Locus ID | 55593 |
| Protein Families | Protease |
| Protein Pathways | RIG-I-like receptor signaling pathway |
| MW | 60 kDa |
| Gene Summary | This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008] |
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