TRM1 (TRMT1) (NM_001136035) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC227256L3V
- LentiORF®
Lenti ORF particles, TRMT1 (Myc-DDK-tagged)-Human TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae) (TRMT1), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 8,930.00
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Specifications
Product Data | |
Product Name | TRM1 (TRMT1) (NM_001136035) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | MRT68; TRM1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001136035 |
ORF Size | 1977 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC227256).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001136035.2 |
RefSeq Size | 2161 bp |
RefSeq ORF | 1980 bp |
Locus ID | 55621 |
Protein Families | Druggable Genome |
MW | 72.2 kDa |
Gene Summary | This gene encodes a tRNA-modifying enzyme that acts as a dimethyltransferase, modifying a single guanine residue at position 26 of the tRNA. The encoded enzyme has both mono- and dimethylase activity when exogenously expressed, and uses S-adenosyl methionine as a methyl donor. The C-terminal region of the encoded protein has both a zinc finger motif, and an arginine/proline-rich region. Mutations in this gene have been implicated in autosomal recessive intellectual disorder (ARID). Alternative splicing results in multiple transcript variants encoding different isoforms. There is a pseudogene of this gene on the X chromosome. [provided by RefSeq, May 2017] |
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