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DKC1 (NM_001142463) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC226852L3V
- LentiORF®
-
Lenti ORF particles, DKC1 (Myc-DDK tagged) - Human dyskeratosis congenita 1, dyskerin (DKC1), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 9,690.00
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| Product Data | |
| Product Name | DKC1 (NM_001142463) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CBF5; DKC; DKCX; NAP57; NOLA4; XAP101 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001142463 |
| ORF Size | 1527 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC226852).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001142463.1 |
| RefSeq ORF | 1530 bp |
| Locus ID | 1736 |
| Protein Families | Druggable Genome |
| MW | 56.9 kDa |
| Gene Summary | This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
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