ZNF451 (NM_015555) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC224347L4V

  • LentiORF®

Lenti ORF particles, ZNF451 (mGFP-tagged)-Human zinc finger protein 451 (ZNF451), transcript variant 2, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 19,570.00


货期*
详询

规格
    • 200 ul

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Specifications

Product Data
Product Name ZNF451 (NM_015555) Human Tagged ORF Clone Lentiviral Particle
Synonyms COASTER; dJ417I1.1
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_015555
ORF Size 3039 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC224347).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_015555.2, NP_056370.2
RefSeq Size 5097 bp
RefSeq ORF 3042 bp
Locus ID 26036
Domains zf-C2H2
Protein Families Transcription Factors
MW 115.6 kDa
Gene Summary E3 SUMO-protein ligase; has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins (PubMed:26524493, PubMed:26524494). Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro). Required for MCM4 sumoylation (By similarity). Has no activity with SUMO1 (PubMed:26524493). Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11' (PubMed:26524493). Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300-mediated acetylation of histone H3 at 'Lys-9' (PubMed:24324267). Plays a role in regulating the transcription of AR targets (PubMed:18656483).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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