TRAF4AF1 (KNSTRN) (NM_033286) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC222981L4V

  • LentiORF®

Lenti ORF particles, KNSTRN (mGFP-tagged) - Human chromosome 15 open reading frame 23 (C15orf23), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 9,120.00


货期*
详询

规格
    • 200 ul

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Specifications

Product Data
Product Name TRAF4AF1 (KNSTRN) (NM_033286) Human Tagged ORF Clone Lentiviral Particle
Synonyms C15orf23; HSD11; SKAP; TRAF4AF1
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_033286
ORF Size 948 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC222981).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_033286.2, NP_150628.2
RefSeq Size 1763 bp
RefSeq ORF 951 bp
Locus ID 90417
MW 35.4 kDa
Gene Summary Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase (PubMed:19667759). Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture (PubMed:19667759, PubMed:22110139). The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments (PubMed:21402792). Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division (PubMed:23035123). May be involved in UV-induced apoptosis via its interaction with PRPF19; however, these results need additional evidences (PubMed:24718257).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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